Articles Tagged with mass tort

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INVOKANA USE MAY LEAD TO FOOT AND LEG AMPUTATIONS

On May 16, the Food and Drug Administration (FDA) issued a new warning about the diabetes drug Invokana. Now, the FDA “has concluded” based on tests that the drug presents an increased risk of foot and leg amputations. Specifically, the FDA safety alert says:

Based on new data from two large clinical trials, the FDA has concluded that the type 2 diabetes medicine canagliflozin (Invokana, Invokamet, Invokamet XR) causes an increased risk of leg and foot amputations. FDA is requiring new warnings, including the most prominent Boxed Warning, to be added to the canagliflozin drug labels to describe this risk.

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Photo by A. Kirk
Did Johnson & Johnson fail to warn women of ovarian cancer risks related to the use of its talcum powder products? For years, Johnson & Johnson has marketed its talcum powder products for feminine hygiene. Yet, the company never warned that the use of talcum powder for feminine hygiene may be linked to ovarian cancer.

Since the early 1970s, numerous studies have indicated an increase in the risk of ovarian cancer with this use of talcum powder. So, why did Johnson & Johnson not warn consumers? Why did Johnson & Johnson continue to make money marketing these products as safe and effective for women? These are questions being raised by women who have suffered ovarian cancer after years of using talcum powder products.

For detailed information, take a look at our page on Talcum Powder Lawsuits located under the Hot Topics section of our firm website. We provide information about talcum powder and the history of its use by Johnson & Johnson. We are happy to answer additional questions as well.

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Our office has closely followed developments with the diabetes drug Invokana. Invokana is in a class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. This is a relatively new class of drugs also including Farxiga, Jardiance, Glyxambi, and Xigduo XR. These drugs treat diabetes by altering kidney function to stop reabsorption of glucose into the patient’s blood stream. We have a page on our firm website discussing these drugs, how they work and their link to diabetic ketoacidosis. Despite being a new drug at the time we published our initial page, Invokana had already been linked to numerous adverse health reports. Since then, even more potential injury risks have emerged. You can read about these developments in several posts on this blog.

In its recent QuarterWatch report, the Institute for Safe Medication Practices (ISMP) calls Invokana a “dangerous gamble.” The ISMP report opens with the following paragraph:

The nation’s gamble in embracing new drugs for long-term use with only short-term clinical testing was most apparent in the rapid acceptance into clinical practice of a new class of oral diabetes drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors. There are now three such agents, canagliflozin (INVOKANA), dapagliflozin (FARXIGA), and empagliflozin (JARDIANCE). Since approval, evidence of multiple safety problems has emerged.
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Invokana continues to be linked to serious health problems. Our office has closely followed developments with the diabetes medication Invokana since it was first approved by the Food and Drug Administration (FDA). Although relatively new to the market, many health injuries are already associated with this drug.

Invokana (canagliflozin) is marketed to treat Type 2 diabetes. The drug is one of a relatively new class of diabetes medications. This class of medications is known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. Other SGLT2 drugs include Jardiance, Farxiga, Glyxambi, and Xigduo XR. These drugs alter kidney function to prevent reabsorption of glucose into the patient’s blood stream. For more detailed information, please read the report on our firm website.

We have watched Invokana closely because of its association with the health problem diabetic ketoacidosis. This is a dangerous adverse health issue suffered by some patients taking Invokana. What is diabetic ketoacidosis? It is a build-up of acid in the blood. Symptoms can include abdominal pain, nausea, fatigue, difficulty breathing and confusion. In May 2015, the FDA issued a safety communication warning patients about the risk of ketoacidosis from Invokana.